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Diabetes

LPLD and Diabetes

People with LPLD have a higher risk of developing type 2 diabetes in middle age, although it can also occur after an episode of pancreatitis or if a women has developed gestational diabetes during pregnancy.

Whether medication is required to manage the diabetes will depend on how severe it is.  It may be possible to manage both type 2 diabetes and LPLD by diet alone, but this will require some further restrictions.

Avoiding simple sugars is  recommended for everyone with LPLD and this becomes more important if diabetes develops, as high blood glucose (also called blood sugar) is turned to fat in the body.  Carbohydrates also raise glucose levels.  Eating smaller meals at regular intervals can help you manage LPLD and diabetes together.

Medications for Diabetes

Metformin:  Is usually the first medicine used to treat type 2 diabetes. It works by reducing the amount of glucose your liver releases into your bloodstream. It also makes your body’s cells more responsive to insulin. Metformin can sometimes cause mild side effects, such as nausea and diarrhoea, and you may not be able to take it if you have kidney damage.

Sitagliptin: Gliptins work by preventing the breakdown of a naturally occurring hormone called GLP-1.
GLP-1 helps the body produce insulin in response to high blood glucose levels, but is rapidly broken down.
By preventing this breakdown, the gliptins (linagliptin, saxagliptin, sitagliptin and vildagliptin) prevent high blood glucose levels, but don’t result in episodes of hypoglycaemia.

Insulin:  Is a hormone made in your pancreas, which helps our bodies use glucose for energy.  Insulin help control blood glucose levels and can be taken either by injection or a pump.